Guide to Exelon Patch
Exelon Patch is a thin, beige, plastic patch that sticks to the skin upon application. Each patch comes individually sealed in a pouch to keep it protected until ready for use. Exelon Patch is supplied in cartons containing 30 patches each. Only 1 Exelon Patch should be worn at a time. Do not open the pouch or remove the Exelon Patch until you are ready to apply it.
Applying the Patch
Choose an area to apply the Exelon Patch
Instructions for Caregivers: Apply Exelon Patch to the upper or lower back if it is likely that the patient will remove it. If this is not a concern, the Exelon Patch can be applied instead to the upper arm or chest. Do not apply the Exelon Patch to areas where it can be rubbed off by tight clothing or belts. Only apply the Exelon Patch to healthy skin that is clean, dry, hairless, and free of redness, irritation, burns or cuts.
Remove the Exelon Patch from the pouch
Carefully cut the pouch along the dotted line to open and remove the Exelon Patch. Save the pouch for later use. Do not cut or fold the Exelon Patch itself.
Remove 1 side of the adhesive liner
A protective liner covers the sticky (adhesive) side of the Exelon Patch. Peel off 1 side of the protective cover. Do not touch the sticky part of the Exelon Patch with your fingers.
Apply the Exelon Patch to your skin
Apply the sticky (adhesive) side of the Exelon Patch to your chosen area of skin and then peel off the other side of the protective cover.
Wash your hands with soap and water right away
If your Exelon Patch falls off, select a new area, and repeat Steps 2 to 5 to apply a new Exelon Patch. Be sure to replace the new Exelon Patch the next day at the same time as usual.
Remove the Exelon Patch from the skin
Gently pull on 1 edge of the Exelon Patch to remove it from your skin.
Throw away the used Exelon Patch
Fold the used Exelon Patch in half (with the sticky sides together) and put it back into the pouch that you saved. Throw away the used Exelon Patch safely and out of the reach of children and pets. Some medicine stays in the patch for 24 hours after you use it and should be folded together (sticky side together) and safely thrown away. Do not try to re-use Exelon Patches.
Wash your hands with soap and water right away
After you remove the Exelon Patch, if any adhesive remains on your skin, you can use soap and water or an oil-based substance (such as baby oil) to remove the adhesive. Alcohol or other dissolving liquids (such as nail polish remover) should not be used.
- Remove the old Exelon Patch each day before applying a new one
- Change your loved one's Exelon Patch every 24 hours at the same time of day. You may write the date and time on the Exelon Patch with a ballpoint pen before applying it to help you remember when to remove it
- Check to see if the Exelon Patch has become loose when your loved one is bathing, swimming, or showering
- Do not apply more than 1 Exelon Patch at a time
- Exelon Patch should never be applied to skin that has cream, lotion, or powder on it
- Avoid applying Exelon Patch to areas on your loved one's body that will rub against tight clothing
- Do not apply Exelon Patch to skin unless it's clean, dry, hairless, and free of redness, irritation, burns, and cuts
- When applying Exelon Patch, avoid using the exact same spot until at least 14 days have passed
- Exelon Patch is for external, skin use only and is not to be ingested
- Do not use overlays, bandages, or tape to secure an Exelon Patch that has become loose or try to reapply an Exelon Patch that has fallen off
If Your Loved One Misses a Dose:
If Your Loved One Misses a Dose:
- If your loved one misses a dose or you forget to change their Exelon Patch, apply their next Exelon Patch as soon as you remember. Do not apply 2 Exelon Patches to make up for the missed dose
- If your loved one misses more than 3 doses of Exelon Patch, call the health care provider before applying a new one, as it may be necessary to restart on a lower dosage strength
- Exelon Patch is designed to deliver medication during the time it is worn. If your loved one's Exelon Patch falls off before its usual replacement time, put a new patch on right away
Why Exelon Patch:
Why Exelon Patch:
- It is approved across all stages of Alzheimer's disease—mild, moderate, and severe
- Exelon Patch has been shown to improve overall cognition and function
- It's the first skin patch proven effective and well tolerated for the treatment of those with Alzheimer's
- Exelon Patch releases medication continuously for 24 hours, so you only need to apply it once a day
Frequently Asked Questions
Does the Exelon Patch come in different doses?
Yes. Exelon Patch is available in three dosage strengths. Doctors prescribe a starting dose of 4.6 mg/24 hours to assess tolerability. If the starting dose is well tolerated after 4 weeks, ask the doctor if introducing the effective dose of 9.5 mg/24 hours is right for your loved one. When greater benefit is needed while on the 9.5 mg/24 hours patch and if still well tolerated for 4 weeks, your loved one's doctor may prescribe the maximum effective dose of 13.3 mg/24 hours.
When should I ask about a higher dose?
After 4 weeks, if your loved one is tolerating the medication, ask the doctor if introducing the effective dose of 9.5 mg/24 hours is right for him or her. Only after treatment has been titrated to a dose of 9.5 mg/24 hours and if greater benefit is needed, will treatment with a dose of 13.3 mg/24 hours be considered. For special populations (patients under 50 kg [110 lb] and patients with mild to moderate hepatic impairment), the HCP will consider using Exelon Patch 4.6 mg/24 hours as the initial and maintenance dose.
Is the Exelon Patch effective for underweight people?
Speak with your doctor if your loved one weighs less than 50 kg/110 pounds, as patients with a body weight below 50 kg/110 pounds may experience more adverse events. Caution should be used in higher than recommended doses. For this population, the HCP will consider using Exelon Patch 4.6 mg/24 hours as the initial and maintenance dose.
Is the Exelon Patch effective for overweight people?
Speak with your doctor if your loved one is overweight. No specific studies investigating overweight people have been conducted.
Is the Exelon Patch still effective if it isn't used for a few months?
Unopened patches can be used up to the expiration date printed on the protective pouch. Once the pouch is opened, the Exelon Patch should be applied immediately. Patches start to lose their medicine when exposed to the air.
Storing the Exelon Patch
How should I store the Exelon Patch?
You should store the Exelon Patch in its unopened, protective pouch at room temperature, between 59° and 86° F, and out of direct sunlight. Be sure to keep the Exelon Patch and all medicines in a safe, secure place out of the reach of children. Throw away any unused medicine after the expiration date.
Can heat affect how the Exelon Patch works?
Exelon Patch should be kept out of excessive sunlight or saunas for long periods of time.
How close can the Exelon Patch be to medicated patches treating other conditions?
This has not been studied; however, we do not recommend overlapping a patch treating something different. Tell the doctor about all other prescription or nonprescription medicines the patient is taking. Exelon products should not be taken at the same time with other medicines that have a similar effect on the body and the brain (cholinomimetic agents) or with anticholinergic medicines. Inform the doctor if the patient needs surgery requiring anesthesia while using the Exelon Patch.
Can I open the Exelon Patch pouches in advance?
No. Once the pouch is opened, the Exelon Patch should be immediately applied. Patches start to lose medicine and become less effective if left opened.
Applying the Exelon Patch
Can I cut the Exelon Patch?
No. The Exelon Patch should not be cut or folded sharply.
Can I write the date on the Exelon Patch?
You may write on the Exelon Patch with a thin ballpoint pen.
What should I do if I forgot to apply the Exelon Patch?
If you have not been applying the Exelon Patch for three days, do not apply the next patch before you have talked to a doctor. If you forgot to apply your loved one's Exelon Patch, remove the old patch and apply a new one immediately. Apply the next patch at the usual time the next day.
Is it OK to shave the application site before I apply the Exelon Patch?
You can shave the application site. However, it's best not to shave the site just prior to application because the skin is often slightly irritated from shaving. If you must shave a site, do so 24 hours before applying the patch.
Can lotions (moisturizing lotions, tanning lotions, etc) affect the Exelon Patch?
Always apply your loved one's patch to clean, dry skin. Do not use creams, oils, powder, or makeup on skin where you are going to put the patch or near a patch he or she is wearing.
How should the Exelon Patch be applied to a person with oily skin?
If your loved one has oily skin, it may be more difficult to keep the patch on. Gently clean the application area with soap and warm water and pat the area dry with a towel. Then immediately apply the patch, pressing firmly.
What should I do if the person being treated is sunburned?
Do not apply the Exelon Patch to oily, broken, burned, sunburned, cut, or irritated skin. Choose another area to apply the patch, as shown in the instructions.
Can the Exelon Patch be applied over a tattoo?
It is not recommended that the patch be applied over a tattoo.
Wearing the Exelon Patch
What should I do if the Exelon Patch keeps falling off?
If the Exelon Patch is not staying on during application, it is possible that the skin is wet or that it is not pressed firmly into place. The patch should be applied and held firmly in place for 30 seconds. Also, some soaps, creams, or lotions may keep the patch from sticking. Check with your doctor or pharmacist to make sure you followed the application instructions correctly. If your Exelon Patch falls off, put on another patch right away and then replace the new patch the next day at the same time as usual. Do not use overlays, bandages, or tape to secure patches that have loosened or reapply patches that have fallen off.
Can the Exelon Patch be worn when bathing, swimming, or in the sun?
Bathing, swimming, or showering should not affect the patch. You can wear the patch under your swimsuit. Make sure the patch does not loosen during these activities. The patch should not be exposed to any external heat sources (eg, excessive sunlight, saunas, solarium) for long periods of time.
How do I remove any adhesive that's left over from the Exelon Patch?
Gently soak the area with warm water and mild soap, or use a small amount of baby oil to remove any residue. If the rings of adhesive become soiled, you may need to use a medical adhesive removal pad that should be available from a pharmacist. Alcohol or other dissolving liquids (nail polish remover or other solvents) may irritate the skin and should not be used.
Does rubbing the Exelon Patch affect how much medicine is released?
Rubbing the Exelon Patch has not been studied.
What should I do if I or my loved one touches the sticky part of the Exelon Patch?
The medicine goes through the adhesive part of the Exelon Patch; therefore, the person who touched the sticky part of the patch should clean his or her hands with soap and water as soon as possible. Avoid contact with the eyes.
What should I do if my loved one places the Exelon Patch in his or her mouth?
Remove the Exelon Patch from your loved one's mouth and contact the doctor immediately. Your loved one may have ingested some of the medicine in the patch; how much depends on how long it was chewed. Make sure that no part of the patch is still in his or her mouth.
What should I do if a child applies or swallows the Exelon Patch?
If a child comes into contact with the Exelon Patch out of its protective pouch, take the patch away and immediately contact a doctor. If a doctor cannot be reached, call the local poison control center, or the emergency department at a local hospital. Used and unused patches should be kept out of the reach of children and disposed of in a place away from children.
Is the Exelon Patch safe for people to wear while undergoing an MRI?
Speak with the doctor if your loved one needs to have an MRI. The Exelon Patch has not been studied in use by people while having an MRI. Please contact your doctor for further information.
Can the Exelon Patch be applied to a person with a pre-existing skin problem?
Do not use Exelon Patch if you: are allergic to rivastigmine, carbamate derivatives, or any of the ingredients in Exelon Patch, or if you have had a skin reaction that:
- Spread beyond the Exelon Patch size
- Had blisters, increased skin redness, or swelling
- Did not get better within 48 hours after you removed the Exelon Patch
Ask your health care provider if you are not sure if you should use Exelon Patch.
What should I do if my loved one experiences a skin reaction?
Some people have had a serious skin reaction called allergic contact dermatitis (ACD) when using Exelon Patch. Stop using Exelon Patch and call your health care provider right away if you experience reactions that spread beyond the patch size, are intense in nature and do not improve within 48 hours after the patch is removed. Symptoms of ACD may be intense and include:
- Itching, redness, swelling, warmth or tenderness of the skin
- Peeling or blistering of the skin that may ooze, drain, or crust over
Is the Exelon Patch available in different colors?
No, it is only available in beige.
Why is the brand name printed on the Exelon Patch?
The name is there for the safety of the patient as well as for those who may come in contact with a discarded patch. Because patches are popular for different treatments, having the name there also makes it easier to tell the Exelon Patch apart from other patches.
- Does the Exelon Patch come in different doses?