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How Exelon Patch Could Help with Alzheimer's

When researching an Alzheimer's treatment for your loved one, you are most likely looking for one that has been proven effective.

The active ingredient in Exelon Patch—rivastigmine—has been studied for over a decade in clinical trials. In these trials, Exelon Patch was shown to help with cognition, which includes things like memory, reasoning, understanding, and communication, as well as doing daily tasks.

How the Exelon Patch Works

Exelon Patch is the only Alzheimer's disease medicine that comes in the form of a patch and the medication from the patch is absorbed through the skin. Exelon Patch releases medication continuously for 24 hours, and can be worn whether or not your loved one has eaten. Only one Exelon Patch should be worn at a time.

Mistakes in using EXELON PATCH have resulted in serious side effects; some cases have required hospitalization, and rarely, have led to death. Most mistakes have involved not removing the old patch when putting on a new one and the use of multiple patches at one time. Only one EXELON PATCH should be worn at a time. If you accidentally apply more than one EXELON PATCH, remove all of them and inform the doctor immediately.

Possible Exelon Patch Side Effects

IMPORTANT SAFETY INFORMATION

EXELON PATCH should not be used if the patient is allergic to any component in EXELON PATCH, including the active ingredient rivastigmine. EXELON PATCH should also not be used if the patient has had a skin reaction that spread beyond the patch size, had blisters, increased skin redness, or swelling, or did not get better within 48 hours after removal of the EXELON PATCH.

Mistakes in using EXELON PATCH have resulted in serious side effects; some cases have required hospitalization, and rarely, have led to death. Most mistakes have involved not removing the old patch when putting on a new one and the use of multiple patches at one time. Only one EXELON PATCH should be worn at a time. If you accidentally apply more than one EXELON PATCH, remove all of them and inform the doctor immediately.

EXELON PATCH can also cause serious stomach side effects, including nausea, vomiting, diarrhea, dehydration, decreased appetite, weight loss, and bleeding in your stomach (ulcers). Dehydration may result from prolonged vomiting or diarrhea and can be associated with serious outcomes. The incidence and severity of these reactions are dose related. For this reason, treatment should be initiated with EXELON PATCH at a dose of 4.6 mg/24 hours and titrated to a dose of 9.5 mg/24 hours, and then 13.3 mg/24 hours, if appropriate. If you have not taken EXELON PATCH for more than 3 days, do not start taking it again until you have talked with a doctor.

Some people have had a serious skin reaction called allergic contact dermatitis (ACD) when using EXELON PATCH. Stop using EXELON PATCH and call your health care provider right away if you experience reactions that spread beyond the patch size, are intense in nature, and do not improve within 48 hours after the patch is removed. Symptoms of ACD may be intense and include itching, redness, swelling, warmth or tenderness of the skin, or peeling or blistering of the skin, which may ooze, drain, or crust over.

The most common side effects of EXELON PATCH include depression, headache, anxiety, dizziness, stomach pain, urinary tract infections, muscle weakness, tiredness, and trouble sleeping.

Weight should be checked while the person is using EXELON PATCH. Weight loss/loss of appetite may occur. People below 50 kg (110 lbs) may experience more side effects and may have to stop using EXELON PATCH due to these side effects.

People at risk for stomach ulcers or who take certain medicines should tell their doctor before starting EXELON PATCH, because serious stomach problems, such as bleeding, may occur.

EXELON PATCH may cause fainting or slow heart rate; people with certain heart conditions should tell their doctor before starting therapy. People with serious lung conditions and difficulty breathing, bladder problems, or seizures should consult their doctor before using EXELON PATCH. Extrapyramidal symptoms (e.g., uncontrollable facial or body movements, including tremor and restlessness) could occur or get worse. Parkinsonian symptoms, particularly tremor, have worsened in Parkinson's disease dementia patients treated with EXELON (rivastigmine tartrate) capsules. Before using EXELON PATCH, people should also tell their doctor about any medical conditions they have, including if they have had a loss of appetite or are losing weight, or if they have had a skin reaction to rivastigmine (the medicine in EXELON PATCH) in the past. People on EXELON PATCH who feel dizzy or drowsy should not drive or use machines.

Tell the doctor about all other prescription or nonprescription medicines the patient is taking.

EXELON PATCH should not be taken at the same time with other medicines that have a similar effect on the body and the brain (cholinomimetic agents) or with anticholinergic medicines. Inform the doctor if the patient needs surgery requiring anesthesia while using EXELON PATCH.

Visually track where you’ve placed the patch on your loved one with our free mobile app.

Visually track where you’ve placed the patch on your loved one with our free mobile app.

Use our monthly tracker sheets for guidance on when and where to apply the Exelon Patch.

Use our monthly tracker sheets for guidance on when and where to apply the Exelon Patch.

8/14 T-EXP-1296017

full Prescribing Information Patient Product Information www.fda.gov/medwatch Patient Assistance Now full Prescribing Information Patient Product Information www.fda.gov/medwatch Patient Assistance Now

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